Treatment of stable angina pectoris with verapamil hydrochloride: a double blind cross-over study
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چکیده
منابع مشابه
Treatment of stable angina of effort with verapamil: a double-blind, placebo-controlled randomized crossover study.
The effects of verapamil were assessed in 26 patients with stable exertional angina pectoris in a double-blind, placebo-controlled, randomized crossover protocol using serial treadmill tests. Verapamil, 480 mg/day, reduced anginal frequency from 5.6 +/- 7.3 to 2.2 +/- 3.9 attacks per week (p less than 0.001) and nitroglycerin consumption from 3.4 +/- 4.9 to 1.2 +/- 2.5 tablets per week (p less ...
متن کاملProphylactic treatment of angina pectoris. A double-blind cross-over comparison of alprenolol and pentanitrol.
Twenty-one patients with angina pectoris took part in a double-blind cross-over comparison of alprenolol (an adrenergic beta-blocker), pentanitrol (pentaerythritol tetranitrate), and placebo. Two-thirds of the patients were clinically improved on alprenolol 100 mg. four times daily, which was found to be significantly better than pentanitrol 30 mg. four times daily and placebo. There was also a...
متن کاملStable Angina Pectoris A Double-Blind, Randomized, Placebo-Controlled Trial
Background. Patients with chronic coronary artery disease exhibit a dysfunctioning endothelium, which may be responsible for exercise-induced platelet activation and expression of a procoagulant moiety. In this study, we evaluated the therapeutic efficacy of a low molecular weight heparin (Parnaparin) in patients with stable angina pectoris. Methods and Results. According to a double-blind, ran...
متن کاملDouble-blind comparison of verapamil and practolol in the treatment of angina pectoris.
In thirteen patients with coronary insufficiency and angina pectoris the therapeutic effects of verapamil, 80 mg three times/day and practolol, 100 mg three times/day, were compared and tested against placebo in a double-blind cross-over fashion. Verapamil proved to be the most efficient drug as regards attack frequency and glyceryl trinitrate consumption as well as physical working capacity, b...
متن کاملA double blind placebo controlled comparison of verapamil, atenolol, and their combination in patients with chronic stable angina pectoris.
The efficacy and effect on cardiac function of verapamil 120 mg three times a day and atenolol 100 mg once a day, singly and in combination, were evaluated in 15 patients with angina pectoris. While they were on the combination treatment four patients withdrew from the study. Episodes of angina pectoris and glyceryl trinitrate consumption were significantly reduced only on the combination. On t...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 1980
ISSN: 1522-9645,0195-668X
DOI: 10.1093/oxfordjournals.eurheartj.a061129